Instructor: Robert Kuhn, PhD 320 Sinsheimer Office Hours     M 2:30 - 3:30 p     229 Thimann     and by appointment coord@darwin.ucsc.edu

TA: Alexandra Dusa Office Hours     M 12:15 - 1:15 p     Th 10 - 11 a     137 Sinsheimer   dusa@chemistry.ucsc.edu

Lecture MWF 11 a - 12:10 p 239 Thimann (after first day)

Discussion 1 W 2 - 3:10 p JBEB 165

Discussion 2 Th 8:30 - 9:40 a JBEB 165

Text: Berg, Tymoczko and Stryer, Biochemistry, 5th ed., WH Freeman, New York, 2002.

Syllabus           

Slides not in textbook:

1       2       3      ||       4       5       6      ||       S6       S8

On reserve in SciLib:
Berg et al. (Stryer), Biochemistry
Voet and Voet, Fundamentals of Biochemistry
Nelson and Cox, Lehninger Principles of Biochemistry
Saltsman et al, Clinical Companion to Accompany Biochemistry (Stryer)

Students: Visit Roche Applied Science to download biochemical pathways wallchart.
It will take about two weeks to arrive, so do not delay.

Oral report            Oral report groups            Midterm histogram            Midterm key

Probs 1        Probs 2        Probs 3        Probs 4        Probs 5        ||         Probs 6        Probs 7        Probs 8        Probs 9       ||        Probs S5      Probs S6      Probs S7      Probs S8     

Enzyme Commission (EC) numbers. Key to all enzymes.

Links to resources elsewhere

Medical Biochemistry lookup page (Indiana State U)

Glycolysis animation (Apple Quick Time). (U of Leeds, UK)

Pyruvate dehydrogenase mechanism animation (U of Guelph, Canada)

glycolysis (Chime). (Carnegie Mellon University)
TCA cycle (Chime). (Carnegie Mellon University)

Follow the carbons around and ID the compounds:
Glycolysis animation. (U of Virginia)
TCA cycle animation. (U of Virginia)

ATP synthase animations      1       2       (UCSC)

lipids. (Queensland U of Technology, Brisbane)

All radicals? or carbocation in cyclooxygenase mechanism ? (U of Minnesota)