Biology 20A - Introduction to Cell and Molecular Biology

Fall 2009

Instructors: Barry Bowman & Al Zahler


Barry Bowman  - Office 426 Sinsheimer Labs

         bowman@biology.ucsc.edu       Tel.  459-2245

         Office hours  -  Wed 12:00 – 1:00 & Thurs  11:00 – 12:00

 

Al ZahlerOffice 451 Sinsheimer Labs

         zahler@biology.ucsc.edu           Tel, 459-5131

         Office hours  -  Thursdays 11:00 - 1:00

 

Key to second exam -   Version A, white  -  Version B, Green

 

Teaching Assistants and Discussion Sections

Text- Life, The Science of Biology by Sadava, 8th edition

 

Self-Assessment – Quiz #1   Quiz 1 with answers

 

Chapter 10, Do Problems 3, 6, 7, 10, 11,  Additional Genetics Problems   Answers

         Note - answer to problem 10b in the book on page G33 has a typo - answer should indicate that

         the female progeny are w+w and w+we (the rest of the answer is correct).

        

Self-Assessment - Quiz#2   Quiz#2 with answers

 

Self-Assessment - Quiz#3

 

 

20A Study Guide -1 '09.pdf

 

20A Study Guide -2 ’09.pdf

 

20A Study Guide -3 ’09.pdf

 

20A Study Guide -4 ’09.pdf  

 

20A Study Guide -5 ’09.pdf

 

20A Study Guide -6 '09.pdf

 

20A Study Guide -7 '09.pdf

 

DNA Replication Movie

 

PCR Animation Movie

 

DNA Sequencing Animation

 

Translation Animation

 

First Exam, with answers     First Exam, multiple choice, yellow version

 

Tenative Schedule  - Note, the schedule for the 2nd half of the course may be modified.

 

Date

Lecture Topic

Reading

Sept. 25

Introduction, The Tree of Life

 

Sept. 28

Basic Chemistry for Biology

Chapt. 2

Sept. 30

The Molecules of Organisms

Chapt. 3

Oct. 2

DNA and RNA

Chapt. 3

Oct. 5

Lipids and Membranes

Chapt. 5

Oct. 7

Membrane Proteins

Chapt. 5

Oct. 9

Procaryotes and Eucaryotes

Chapt. 4

Oct. 12

Organelles and the Cytoskeleton

 

Oct. 14

Energy and Metabolism

Chapt. 6

Oct. 16

Exam

 

Oct. 19

Glycolysis and the Krebs Cycle

Chapt. 7

Oct. 21

Electron Transport and ATP Synthesis

 

Oct. 23

The Cell Cycle

Chapt. 9

Oct. 26

Mitosis

 

Oct. 28

Meiosis

 

Oct. 30

Mendel and the Gene

Chapt. 10

Nov. 2

Chromosomes, Linkage

 

Nov. 4

Gene Function - DNA as Genetic Material

Chapt. 11.1, 11.2

Nov. 6

DNA Synthesis

Chapt. 11.3

Nov. 9

DNA Mutation and Repair, PCR

Chapt. 11.4, 11.5

Nov. 11

Holiday

 

Nov. 13

DNA Sequencing, Transcription

Chapt. 11.5, 12.2, 12.3

Nov. 16

Exam

 

Nov. 18

RNA Processing

Chapt. 14.2, 14.3

Nov. 20

tRNA

Chapt 12.3, 12.4

Nov. 23

Ribosomes

Chapt 12.4, 12.5, 12.6

Nov. 25

Prokaryotic Gene Regulation

Chapt. 13

Nov. 30

Eukaryotic Gene Regulation

Chapt. 14

Dec. 2

Methods of Molecular Biology

Chapt. 16, 17

Dec. 4

Methods of Molecular Biology

 

 

 

 

Dec. 9

Final Exam,  4pm – 7pm

 

 

Policy on Cheating

 

Books I Recommend

 

Good sites for animations and movies.

            http://multimedia.mcb.harvard.edu/media.html

        

         http://www.johnkyrk.com/index.html

 

Text: Life, The Science of Biology, by Sadava et al.

The bookstore will carry a paperback version that has the first third of the book.  This will work fine for Bio20A.  You can also get the whole book.  We plan on using this same text for Bio 20B and Bio 20C.  The 8th edition is most recent, but editions 7 and 6 are fine also for Bio 20A.  I don’t know if the instructors in  Bio 20B&C required the 8th edition, but I doubt that it makes much difference.  You can find new or used copies of the older additions for greatly reduced prices.

 

How to do well in this course.

Bio 20A  provides information essential for all areas of biology.  You should plan to spend 15 hours per week on this course.  This includes 5 hours for lectures, discussion sections and office hours, and 10 hours for independent study. 

Read all the information in the textbook.  Do this carefully and make sure you understand before moving on to new material.  If you don't understand a topic ask about it in sections or come to my office hours.

Take notes in class.  This helps you to organize the material and to stay focused on the lecture.   If you have questions, ask, even though it is a big class.    Of course, come to class!  Go to your discussion section. I have found a high correlation between attendance and performance.   Sit where you can see and hear well.

Use the Study Guide.  I will periodically provide an outline of "What you need to know."  Go through the Study Guide and explain each of the topics to yourself, in your our words.  One of the best ways to determine your level of understanding is to put into words how you would teach this material to someone else.  If you can't explain it, then you don't really understand it.

Don't get behind.  Ten weeks goes by fast. 

 

Link for one-letter amino acid code --   http://wwwchem.csustan.edu/chem4400/code.htm